Curriculum Structure

1) Required courses 8 credits
2) Elective courses not less than 4 credits
3) Thesis 36 credits

Total not less than 48 Credits

Master to Ph.D.

CODE

SUBJECT

CREDIT(S)

LECTURE(H)

LAB(H)

Required Course

     

SIPM 603

Seminar in Pharmacology and New Drug Development

3

45

SIPM 604

New Drug Development II 

3

45

SIPM 607

Seminar in Drug Discovery and Development

2

30

Elective Course (not less than 4 credits)

     

SIPM 514

Fundamentals of Medical Pharmacology

3

45

SIPM 515

Medical Pharmacology and Therapeutics

3

45

SIPM 516

Fundamental Principles in Systems Pharmacology

3

45

SIPM 517

Advanced Quantitative Techniques in Systems Pharmacology

3

45

SIPM 608

Frontier Research in Redox and Bioenergetic Pharmacology

1

15

SIPM 609

Precision Oncology Concepts from Real-World Case Studies

3

45

SIPM 610

Laboratory in Systems Pharmacology I

2

60

SIPM 611

Laboratory in Systems Pharmacology II

2

60

SIPM 613

Frontier Experimental Methodology in Pharmacology and New Drug Development

3

30

30

MTID 617 Bioinformatics  2 15 30
SIBS 512 Precision Medicine 2 15 30
SIIM 617 Advanced Flow Cytometry 2 30

Thesis

     

SIPM 699  

Dissertation

36

108

SIPM 898

Dissertation

48

144

Required Courses

SIPM603: New Drug Development I 3(3-0-6)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 603 New Drug Development I 3 45

Course Description: 

Review principles and research methodologies of the complete new drug discovery and development in preclinical studies including in-depth pharmacological research in both in vitro and in vivo studies; modeling design; ethical consideration, and international regulations

Learning Outcome(s) : 

SIPM604: New Drug Development II 3(3-0-6)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 513 New Drug Development II 3 45

Course Description: 

All essential principles of clinical drug development: applied clinical pharmacology for first-in-human and early phase trials; study designs of clinical trial phase I, II, and III; ethical and international regulations for new drug approval; post-marketing studies including pharmacoepidemiology, pharmacoeconomics, and drug cycle. 

Learning Outcome(s) : 

SIPM607: Seminar in Drug Discovery and Development 2(2-0-4)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 607 Seminar in Drug Discovery and Development 2 30

Course Description: 

Advancement of various aspects of biopharmaceutical research and industry: gene editing technologies (such as CRISPR/Cas9), growth in immunooncology, targeting ribonucleic acid (RNA); an increasing focus on human microbiome; growing excitement about artificial intelligence (AI) for drug discovery/development; novel antibiotics for the threat of bacterial resistance; a controversial rapid growth of medical cannabis.

Learning Outcome(s) : 

Elective Course (not less than 4 credits)

SIPM514: Fundamentals of Medical Pharmacology 3(3-0-6)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 514 Frontier Research in Medical Pharmacology 3 45

Course Description: 

Basic pharmacology, toxicology, biostatistics, and pharmacogenomics; regulatory science, the process of the preclinical and clinical drug development.

Learning Outcome(s) : 

SIPM515: Medical Pharmacology and Therapeutics 3(3-0-6)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 515 Medical Pharmacology and Therapeutics 3 45

Course Description: 

Mechanisms of drugs interacting with systems of the human body; the components of molecule, enzyme, and pathway involving each system in the human body; the identified possible targets of diseases for the current treatment and the future treatment.

Learning Outcome(s) : 

SIPM516: Fundamental Principles in Systems Pharmacology 3(3-0-6)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 516 Fundamental Principles in Systems Pharmacology 3 45

Course Description: 

The system-level reasoning of complex biological processes; advanced omics techniques for the system pharmacology research; basic handling of big data from omic measurement; computational concepts in the biomolecular dynamics, signaling cascades, feedback regulations and biological noises.

Learning Outcome(s) : 

SIPM517: Advanced Quantitative Techniques in Systems Pharmacology 3(3-0-6)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 517 Advanced Quantitative Techniques in Systems Pharmacology 3 45

Course Description: 

Hands-on skills on data normalization and preprocessing; advanced computational principles for analyzing and visualizing complex high-throughput omics data from genomics, transcriptomics, and antibody-based proteomics; the dimensional reduction; network analysis; data clustering; analysis and management of clinical data.

Learning Outcome(s) : 

SIPM608: Frontier Research in Redox and Bioenergetic Pharmacology 1(1-0-2)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 608 Frontier Research in Redox and Bioenergetic Pharmacology 1 15

Course Description: 

Free radicals and reactive oxygen species (ROS) production; antioxidant defense systems; redox signaling pathway mechanisms; oxidative stresses and their effects in aging, cancer, metabolic diseases and other pathological conditions; ATP production mechanisms of the cell; mitochondrial dysfunctions in diseases; current advanced researches and therapeutic applications in redox and bioenergetic pharmacology.

Learning Outcome(s) : 

SIPM609: Precision Oncology Concepts from Real-World Case Studies 3(3-0-6)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 609 Precision Oncology Concepts from Real-World Case Studies 3 45

Course Description: 

Oncogene addiction; Synthetic lethality; Intratumor heterogeneity; Immune checkpoint blockade; Neoantigen prediction and cancer vaccine; Acquired vulnerability; Genetic and nongenetic resistance mechanisms; Molecularbased and tumoragnostic biomarkers; Panomic subgrouping approaches; Cancer immunotherapy biomarkers; Umbrella and basket trials; Genomic tumor board.

Learning Outcome(s) : 

SIPM610: Laboratory in Systems Pharmacology I 2(0-4-2)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 610 Laboratory in Systems Pharmacology I 2 30

Course Description: 

MATLAB, Tellurium and R languages: implement functions, solve ordinary differential equations, build tellurium-based dynamical models, and develop regression models.

Learning Outcome(s) : 

SIPM611: Laboratory in Systems Pharmacology II 2(0-4-2)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 611 Laboratory in Systems Pharmacology II 2 30

Course Description: 

R and Python languages: pre-process large dataset, visualize big data, process different omic databases, Implement quantitative image processing, machine-learning tools for data mining.

Learning Outcome(s) : 

SIPM613: Frontier Experimental Methodology in Pharmacology and New Drug Development
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 613 Frontier Experimental Methodology in Pharmacology and New Drug Development 3 30 30

Course Description: 

Application of updated research methodology in pharmacology and new drug development; transcriptome and proteome profiling technologies; updated techniques for active principle analysis; updated techniques for protein and nucleic acid analysis; updated techniques in metabolomics and pharmacokinetics; updated imaging techniques in pharmacology; updated techniques for genetic perturbation; the updated animal research in pharmacology and new drug development.

Learning Outcome(s) : 

MTID 617: Bioinformatics
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 613 Bioinformatics 2 15 30

Course Description: 

Data, database, bioinformatic tools; application for genetic materials analysis, proteins, biomolecules, and chemicals.

Learning Outcome(s) : 

SIBS 512: Precision Medicine
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIBS 512 Precision Medicine 2 15 30

Course Description: 

Concepts of precision medicine, stratifying patients using next-generation sequencing data and clinical data, applying other ‘omic’ methodology to complement genomic blind plots for identifying new diagnostic and prognostic markers, case studies in tumor profiling, using blood-based gene expression profiles in cancer prognosis, building and visualizing omic data, issues on patient privacy, ethical challenges in precision medicine.

Learning Outcome(s) : 

SIIM 617: Advanced Flow Cytometry
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIIM 617 Advanced Flow Cytometry 2 30

Course Description: 

Introduction to advanced flow cytometry; flow cytometric operation; high dimensional data analysis; flow cytometric experimental design; advanced flow cytometry techniques for research; quality control in flow cytometry; flow cytometric data presentation; specific cell subset isolation by flow cytometric-based cell sorting; recent advance in flow cytometry.

Learning Outcome(s) : 

Thesis

SIMP699: Dissertation 36(0-108-0)

CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 699 Dissertation36   108

In-depth research in novel knowledge which benefits pharmacology and is research ethical, thesis writing, research article writing and publication, ethics in research publication.

 

SIMP898: Thesis 48(0-144-0)

CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 898 Thesis 48 144

In-depth research in novel knowledge which benefits pharmacology and is research ethical, thesis writing, research article writing and publication, ethics in research publication.