Curriculum Structure

1) Required courses 14 credits
2) Elective courses not less than 10 credits
3) Thesis 48 credits

Total not less than 72 Credits

Bachelor to Ph.D.

CODE

SUBJECT

CREDIT(S)

LECTURE(H)

LAB(H)

Required Course

     

SIID 501

Molecular and Cellular Basis of Biomedicine

3

30

30

SIPM 603

New Drug Development I

3

45

SIPM 604

New Drug Development II 

3

45

SIPM 607

Seminar in Drug Discovery and Development

2

30

SIPM 612

Frontier Research in Pharmacology and New Drug Development

3

45

Elective Course (not less than 13 credits)

     

SIPM 514

Fundamentals of Medical Pharmacology

3

45

SIPM 515

Medical Pharmacology and Therapeutics

3

45

SIPM 516

Fundamental Principles in Systems Pharmacology

3

45

SIPM 517

Advanced Quantitative Techniques in Systems Pharmacology

3

45

SIPM 608

Frontier Research in Redox and Bioenergetic Pharmacology

1

15

SIPM 609

Precision Oncology Concepts from Real-World Case Studies

3

45

SIPM 610

Laboratory in Systems Pharmacology I

2

60

SIPM 611

Laboratory in Systems Pharmacology II

2

60

SIPM 613

Frontier Experimental Methodology in Pharmacology and New Drug Development

3

30

30

MTID 617

Bioinformatics 

2

15

30

SIBS 512

Precision Medicine

2

15

30

SIIM 617

Advanced Flow Cytometry

3

30

Thesis

     

SIPM 799

Dissertation

48

144

SIPM 899  

Dissertation

72

216

Core courses

SIID501: Molecular and Cellular Basis of Biomedicine 3 (2-2-5)

Biomolecules, cell structure and function, genetic materials, regulation of gene expression, structure and mechanism of enzyme, membrane biology, cell communication, cell signaling, energy metabolism, cell proliferation, cell differentiation, cell death, cancer, basic immune response, host – pathogen interaction, basic gene, protein, cellular and immunological methods in biomedical research

CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIID 501 MOLECULAR AND CELLULAR BASIS OF BIOMEDICINE 3 30 30

Required Courses

SIPM603: New Drug Development I 3(3-0-6)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 603 New Drug Development I 3 45

Course Description: 

Review principles and research methodologies of the complete new drug discovery and development in preclinical studies including in-depth pharmacological research in both in vitro and in vivo studies; modeling design; ethical consideration, and international regulations

Learning Outcome(s) : 

SIPM604: New Drug Development II 3(3-0-6)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 513 New Drug Development II 4 45

Course Description: 

All essential principles of clinical drug development: applied clinical pharmacology for first-in-human and early phase trials; study designs of clinical trial phase I, II, and III; ethical and international regulations for new drug approval; post-marketing studies including pharmacoepidemiology, pharmacoeconomics, and drug cycle. 

Learning Outcome(s) : 

SIPM607: Seminar in Drug Discovery and Development 2(2-0-4)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 607 Seminar in Drug Discovery and Development 3 30

Course Description: 

Advancement of various aspects of biopharmaceutical research and industry: gene editing technologies (such as CRISPR/Cas9), growth in immunooncology, targeting ribonucleic acid (RNA); an increasing focus on human microbiome; growing excitement about artificial intelligence (AI) for drug discovery/development; novel antibiotics for the threat of bacterial resistance; a controversial rapid growth of medical cannabis.

Learning Outcome(s) : 

SIPM612: Frontier Research in Pharmacology and New Drug Development 3(3-0-6)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 612 Frontier Research in Pharmacology and New Drug Development 3 45

Course Description: 

Updated pharmacological research principles, and techniques crucial for thesis development; new drug development, advanced pharmacokinetics, targeted therapeutics, big data handling, clinical and translational study design, biostatistics, systems pharmacology, redox pharmacology, inflammation pharmacology, cancer research,  animal research, immunopharmacological research,

Learning Outcome(s) : 

Elective Course (not less than 13 credits)

SIPM514: Fundamentals of Medical Pharmacology 3(3-0-6)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 514 Frontier Research in Medical Pharmacology 3 45

Course Description: 

Basic pharmacology, toxicology, biostatistics, and pharmacogenomics; regulatory science, the process of the preclinical and clinical drug development.

Learning Outcome(s) : 

SIPM515: Medical Pharmacology and Therapeutics 3(3-0-6)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 515 Medical Pharmacology and Therapeutics 3 45

Course Description: 

Mechanisms of drugs interacting with systems of the human body; the components of molecule, enzyme, and pathway involving each system in the human body; the identified possible targets of diseases for the current treatment and the future treatment.

Learning Outcome(s) : 

SIPM516: Fundamental Principles in Systems Pharmacology 3(3-0-6)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 516 Fundamental Principles in Systems Pharmacology 3 45

Course Description: 

The system-level reasoning of complex biological processes; advanced omics techniques for the system pharmacology research; basic handling of big data from omic measurement; computational concepts in the biomolecular dynamics, signaling cascades, feedback regulations and biological noises.

Learning Outcome(s) : 

SIPM517: Advanced Quantitative Techniques in Systems Pharmacology 3(3-0-6)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 517 Advanced Quantitative Techniques in Systems Pharmacology 3 45

Course Description: 

Hands-on skills on data normalization and preprocessing; advanced computational principles for analyzing and visualizing complex high-throughput omics data from genomics, transcriptomics, and antibody-based proteomics; the dimensional reduction; network analysis; data clustering; analysis and management of clinical data.

Learning Outcome(s) : 

SIPM608: Frontier Research in Redox and Bioenergetic Pharmacology 1(1-0-2)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 608 Frontier Research in Redox and Bioenergetic Pharmacology 1 15

Course Description: 

Free radicals and reactive oxygen species (ROS) production; antioxidant defense systems; redox signaling pathway mechanisms; oxidative stresses and their effects in aging, cancer, metabolic diseases and other pathological conditions; ATP production mechanisms of the cell; mitochondrial dysfunctions in diseases; current advanced researches and therapeutic applications in redox and bioenergetic pharmacology.

Learning Outcome(s) : 

SIPM609: Precision Oncology Concepts from Real-World Case Studies 3(3-0-6)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 609 Precision Oncology Concepts from Real-World Case Studies 3 45

Course Description: 

Oncogene addiction; Synthetic lethality; Intratumor heterogeneity; Immune checkpoint blockade; Neoantigen prediction and cancer vaccine; Acquired vulnerability; Genetic and nongenetic resistance mechanisms; Molecularbased and tumoragnostic biomarkers; Panomic subgrouping approaches; Cancer immunotherapy biomarkers; Umbrella and basket trials; Genomic tumor board.

Learning Outcome(s) : 

SIPM610: Laboratory in Systems Pharmacology I 2(0-4-2)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 610 Laboratory in Systems Pharmacology I 2 30

Course Description: 

MATLAB, Tellurium and R languages: implement functions, solve ordinary differential equations, build tellurium-based dynamical models, and develop regression models.

Learning Outcome(s) : 

SIPM611: Laboratory in Systems Pharmacology II 2(0-4-2)
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 611 Laboratory in Systems Pharmacology II 2 30

Course Description: 

R and Python languages: pre-process large dataset, visualize big data, process different omic databases, Implement quantitative image processing, machine-learning tools for data mining.

Learning Outcome(s) : 

SIPM613: Frontier Experimental Methodology in Pharmacology and New Drug Development
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 613 Frontier Experimental Methodology in Pharmacology and New Drug Development 3 30

30

Course Description: 

Application of updated research methodology in pharmacology and new drug development; transcriptome and proteome profiling technologies; updated techniques for active principle analysis; updated techniques for protein and nucleic acid analysis; updated techniques in metabolomics and pharmacokinetics; updated imaging techniques in pharmacology; updated techniques for genetic perturbation; the updated animal research in pharmacology and new drug development.

Learning Outcome(s) : 

MTID 617: Bioinformatics
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
MTID 617 Bioinformatics  2 15

30

Course Description: 

Data, database, bioinformatic tools; application for genetic materials analysis, proteins, biomolecules, and chemicals.

Learning Outcome(s) : 

SIBS 512: Precision Medicine
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIBS 512 Precision Medicine 2 15

30

Course Description: 

Concepts of precision medicine, stratifying patients using next-generation sequencing data and clinical data, applying other ‘omic’ methodology to complement genomic blind plots for identifying new diagnostic and prognostic markers, case studies in tumor profiling, using blood-based gene expression profiles in cancer prognosis, building and visualizing omic data, issues on patient privacy, ethical challenges in precision medicine.

Learning Outcome(s) : 

SIIM 617: Advanced Flow Cytometry
CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIIM 617 Advanced Flow Cytometry 2 30

Course Description: 

Introduction to advanced flow cytometry; flow cytometric operation; high dimensional data analysis; flow cytometric experimental design; advanced flow cytometry techniques for research; quality control in flow cytometry; flow cytometric data presentation; specific cell subset isolation by flow cytometric-based cell sorting; recent advance in flow cytometry.

Learning Outcome(s) : 

Thesis

SIMP799: Dissertation 48(0-144-0)

CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 799 Dissertation 48 144

In-depth research in novel knowledge which benefits pharmacology and is research ethical, thesis writing, research article writing and publication, ethics in research publication.

 

SIMP899: Dissertation 78(0-216-0)

CODE SUBJECT CREDITS LECTURE(h) LAB(h)
SIPM 899 Dissertation 72 216

In-depth research in novel knowledge which benefits pharmacology and is research ethical, thesis writing, research article writing and publication, ethics in research publication.